Pulmonary, Immune, and Dermal Effects of Welding Fumes
Project Information
| Principal Investigator | James Antonini |
| Institution | National Institute for Occupational Safety and Health |
| Project URL | View |
| Relevance to Implications | High |
| Class of Nanomaterial | Incidental Nanomaterials |
| Impact Sector | Human Health |
| Broad Research Categories |
Exposure Hazard Characterization |
| NNI identifier |
Funding Information
| Country | USA |
| Anticipated Total Funding | n/a |
| Annual Funding | n/a |
| Funding Source | NIOSH |
| Funding Mechanism | Intramural |
| Funding Sector | Government |
| Start Year | 2002 |
| Anticipated End Year | 2007 |
Abstract/Summary
The goals of this project are to (1) design, construct, and test a generation system that would produce a consistent fume (concentration and characteristics) for inhalation exposure to rats; (2) characterize the welding fume as generated and within the inhalation chamber; (3) determine how characteristics change with distance from the generator source; (4) expose rats by inhalation to welding fume; (5) characterize pulmonary, immune, and dermal reactions to exposure; (6) determine the dose-response and time-course of these reactions; and (7) determine the effect of welding process (mild steel versus stainless steel) on pulmonary response.
