Generation and Characterization of Occupationally Relevant Airborne Nanoparticles
Project Information
Principal Investigator | Doug Evans |
Institution | National Institute for Occupational Safety and Health |
Project URL | View |
Relevance to Implications | High |
Class of Nanomaterial | Incidental Nanomaterials |
Impact Sector | Human Health |
Broad Research Categories |
Generation, Dispersion, Transformation etc. Characterization |
NNI identifier |
Funding Information
Country | USA |
Anticipated Total Funding | n/a |
Annual Funding | n/a |
Funding Source | NIOSH |
Funding Mechanism | Intramural |
Funding Sector | Government |
Start Year | 2004 |
Anticipated End Year | 2009 |
Abstract/Summary
Mounting evidence shows that the toxicity of some aerosols may be closely associated with the number or surface area of inhaled particles. Low-solubility ultrafine (typically smaller than 100 nm) and high-specific, surface-area particles are of particular concern. This project is part of a wider research program aimed at studying the toxicity of workplace-related aerosols in this category, including those associated with nanotechnology. Methods are being developed to generate and deliver well characterized particles to exposure systems, enabling particle characteristics responsible for specific toxic responses to be investigated in a systematic manner. The research includes the development of off-line and on-line aerosol and particle characterization techniques, including methods to measure aerosol surface area, and methods to characterize the composition and structure of nanometer-diameter particles.