Pulmonary Effects of Exposure to Various Nanoparticles

Project Information

Principal Investigator	Dale Porter
Institution	National Institute for Occupational Safety and Health
Project URL	View
Relevance to Implications	High
Class of Nanomaterial	Engineered Nanomaterials
Impact Sector	Human Health
Broad Research Categories	Exposure
NNI identifier

Funding Information

Country	USA
Anticipated Total Funding	n/a
Annual Funding	n/a
Funding Source	NIOSH
Funding Mechanism	Intramural
Funding Sector	Government
Start Year	2005
Anticipated End Year	2008

Abstract/Summary

The purpose of this project is to evaluate several types of nanoparticles for toxicity in the conducting airways and alveolar region of the lung, and to understand their mechanisms of toxicity by comparing the effects of pulmonary exposure to fine versus ultrafine metal oxide particles. The data obtained will contribute to the development of a toxicological database necessary for hazard identification and to the NIOSH Nanotechnology and Health and Safety Research Program. The project will provide data to NIOSH, OSHA, and EPA for nanoparticle exposure risk assessment and prevention.